Classify Rx on Instagram: "📍 Blood-Brain Barrier Penetration Domperidone = minimal BBB crossing → lower CNS side effects (less EPS, sedation, drowsiness). Metoclopramide = readily crosses BBB → higher risk of extrapyramidal symptoms (dystonia, akathisia, tardive dyskinesia). 📍 Extrapyramidal Risk Trade-off Metoclopramide’s central D2 antagonism causes acute dystonia, parkinsonism, and irreversible tardive dyskinesia (especially elderly, prolonged use). Domperidone’s peripheral action spares pa

Ischemic stroke: Causes, symptoms, and risk factors

Extrapyramidal symptoms (EPS) are some of the most common, and most misinterpreted, medication side effects in psychiatry. They are often mistaken for anxiety, agitation, depression, negative symptoms, or even worsening psychosis, leading to treatment decisions that can actually make patients worse. In this video, I break down down EPS in simple, practical language so clinicians can recognize them early and manage them safely. You’ll learn: • What extrapyramidal symptoms (EPS) are, and why they