A primer on the Ubiquitin-proteasome System • iBiology
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A primer on the Ubiquitin-proteasome System • iBiology
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Ubiquitin antibodies from Thermo Fisher Scientific
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Ubiquitin antibodies from Thermo Fisher Scientific
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In eukaryotic cells, the major pathway for the selective degradation of cytosolic and nuclear proteins employs a molecule called ubiquitin. Ubiquitin is a 76-amino-acid polypeptide that is highly conserved in all eukaryotes. When attached in chains to proteins, ubiquitin targets the proteins for rapid proteolysis. A ubiquitin molecule is attached by its carboxy-terminal amino acid—which is a glycine—to the amino group of a lysine in the protein of interest. In turn, this first ubiquitin molecule
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How does ubiquitin attach itself to a target protein?... | Filo
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