A signal-processing–based framework converts DNA sequences into numerical signals to identify protein-coding regions. By integrating spectral analysis and SVM classification, the approach improves ...
Abstract: The tumor microenvironment is a dynamic eco system where cellular interactions drive cancer progression. However, inferring cell-cell communication from non-spatial scRNA-seq data remains ...
Ongoing work in functional annotations of genomes has generated rich datasets. We propose a method to link extensive functional annotations to genotype-to-phenotype associations. This method ranks ...
ABSTRACT: The absence of the atp8 gene in the mitochondrial genomes of Platyhelminthes and certain other mollusks has garnered significant attention in recent years. Growing evidence suggests that ...
Introduction: Comprehensive functional annotation of the genome is crucial for elucidating the molecular mechanisms underlying complex traits and diseases. Although functional annotation has been ...
1 State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, China. 2 Tobacco Research Institute of Hubei Province, Wuhan, China. The rhizosphere ...
Abstract: The process of functional annotation of human genetic variants is important for some significant biomedical tasks like understanding functional genomics and gene-disease associations.
SurvSTAAR is an R package for performing variant-Set Test for Association using Annotation infoRmation (STAAR) procedure in whole-genome sequencing (WGS) studies in time-to-event traits. SurvSTAAR is ...
To understand the molecular mechanism underlying salt stress response in radish, iTRAQ-based proteomic analysis was conducted to investigate the differences in protein species abundance under ...
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