Serotonin is one of the primary chemicals that the brain uses to influence mood and behavior, and is a key target for psychiatric drugs. But to aid in the design of improved drugs scientists need to ...

Receptors mediate the transmission of information between nerve cells. The release of serotonin alters nerve cell activities throughout the brain. At least 14 types of serotonergic receptors can be ...

With full genetic control and visibility into neural activity and behavior, scientists map out chemical's role in behavior. Because serotonin is one of the primary chemicals the brain uses to ...

Activation of the serotonin receptor, 5-HT1A, has been shown to regulate mood and cognition. The receptor is the primary target of buspirone, vilazodone, and gepirone, FDA-approved medications for the ...

Researchers at Baylor College of Medicine, the University of Cambridge in the U.K. and collaborating institutions have shown that serotonin 2C receptor in the brain regulates memory in people and ...

Researchers at the Icahn School of Medicine at Mount Sinai have shed valuable light on the complex mechanisms by which a class of psychedelic drugs binds to and activates serotonin receptors to ...

January 18, 2010 — Individuals with treatment-resistant depression tend to have the G/G genotype associated with higher levels of 5-HT 1A autoreceptors, and turning off some of those autoreceptors ...

Philadelphia, June 13, 2023 – Cognitive deficits accompany mood disorders and other psychiatric conditions, often with debilitating effects. Limited treatments currently exist, but studies in animals ...

A collaborative study involving Baylor College of Medicine, the University of Cambridge and the University of Exeter Medical School reveals a new gene associated with obesity and maladaptive behavior.