Unusual KRAS mutation in pancreatic cancer may explain less aggressive tumors

A study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, reveals why a specific gene ...
GEN

Mapping Cancer Drug Resistance Mutations and Mechanisms

A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...
News-Medical.Net on MSN

Single-cell technique maps pre-malignant gene mutations in solid tissues

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...
Wired

For the First Time, Mutations in a Single Gene Have Been Linked to Mental Illness

Research links variations in the gene GRIN2A to a higher risk of developing schizophrenia and other forms of mental illness. The GRIN2A gene regulates communication between neurons by producing the ...
Phys.org

Mutations that affect protein stability follow simple math rules, study shows

In a study published in the journal Nature, researchers from the Center for Genomic Regulation (CRG) and the Wellcome Sanger Institute have discovered that mutations affect protein stability following ...
Fred Hutch

Surprising findings about blood cell mutations bode well for transplant recipients

After an allogeneic stem cell transplant, a recipient’s body faces a daunting task: rebuilding the person’s blood-forming and immune systems from the ground up from a relatively small number of “seed” ...