In a recent paper in ACS Central Science, researchers report a strategy for targeting covalent modifications to specific sites on proteins. The modifier molecules use an antibody to target a protein ...

The paradigm in nutritional science is shifting from studying isolated nutrients to understanding the complex food matrix.

A research team has developed an innovative technique that enables precise modification of specific proteins within complex biological environments. A research team led by Professor Seung Soo Oh and ...

The newly launched Hyku Biosciences provides a platform for covalent drug development which may be a better approach for treating diseases like cancer. One of Hsu's SuTEx molecules targets sites on ...

Proteins are important molecules—but they aren’t the only molecules in a cell, and they don’t operate alone. In a new preprint, the team behind the protein structure prediction software RoseTTAFold ...

Terremoto Biosciences is a company making waves in the drug development world. They’re using a pretty cool approach to create new medicines, focusing on how molecules interact at a chemical level.

The Flagship Pioneering spinout uses permanent bonds to target shallow pockets, drastically expanding the druggable universe for small molecules.

Covant Therapeutics, Roivant’s latest spin-off company, will have a major partner with whom to explore the benefits of covalency, courtesy of an exclusive research pact and licensing deal with ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...