Traditional epidemiological studies have identified numerous potential risk factors, but observational studies have struggled to establish causal links due to confounding factors and reverse causation ...

In Mendelian inheritance patterns, you receive one version of a gene, called an allele, from each parent. These alleles can be dominant or recessive. Non-Mendelian genetics don’t completely follow ...

Since its emergence in December 2019, in Wuhan, China, the coronavirus disease 2019 (COVID-19), caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to more ...

Mendelian randomization, a powerful tool in medical research, helps us understand whether certain factors truly cause disease. This technique uses genetic variations as "natural experiments" to reveal ...

The comparison of publications/citations in Mendelian randomisation from 2015 to 2024. On the top, it reflects the trend of total publications and citations each year. The keywords in this field are ...

The study found that people with lower vitamin D levels had higher levels of CRP. This means there is a one-way connection—low vitamin D leads to more inflammation. This is not just a coincidence. The ...

Introduction to Mendelian randomization, the problems with using traditional observational studies to investigate causality, and Randomized controlled trials as the gold standard for causal research.