Learning more about the mTOR complex and how it works is a stepping stone for others who might look for cancer therapies or ways to help treat diabetes and other diseases. In the world of biology, ...

Individuals with certain comorbidities, such as obesity and diabetes, are at a higher risk of being severely infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal ...

Sepsis, one of the most acute and serious disease complications in the intensive care unit, is caused by various infections and results in life-threatening organ dysfunction. The intestinal barrier ...

Prognostic value of hedgehog signaling in cervical carcinoma. Background: Although improvements in the treatment of ovarian cancer have increased the global prognosis, the metastatic disease is still ...

Network map of 29 authors with frequency greater than five. Nodes represent authors, and the larger the node, the higher the number of papers. The lines represent collaborations with other authors, ...

A sequential doublet chemotherapy regimen in patients (pts) with advanced endometrial adenocarcinoma (EC) and gynecological mixed müllerian tumors (MMT). Maintaining activity with tolerability? No ...

Investigators at KU Leuven have discovered that although mTOR signaling was important in primary breast tumors and lung metastases alike, the signals that activated mTOR were different between the two ...

CePA exerts a liver-targeted mTOR repressive function, alleviating MASH progression and fat accumulation in high-fat diet-fed mice. Metabolic dysfunction-associated steatohepatitis (MASH) is one of ...