The UK’s Medicines and Healthcare Regulatory Agency (MHRA) has warned men taking epilepsy medication valproate and their partners to use effective contraception, due to risks associated with ...

Paternal use of the anti-seizure medication valproate during spermatogenesis was not associated with a risk of congenital malformations or neurodevelopmental disorders in offspring, an observational ...

The Medicines and Healthcare products Regulatory Agency (MHRA) has recommended that men taking valproate, and their female partners, should use effective contraception throughout the time they are on ...

Men taking sodium valproate are being warned to use contraception while on the medicine, because of "a potential small increased risk" of neurodevelopmental disorders in their future children, ...

New guidance to support regulations around the use of valproate in women and girls of child bearing age with epilepsy has been published by specialists from 13 UK healthcare bodies including seven ...

The Medicines and Healthcare products Regulatory Agency (MHRA) has instructed healthcare organisations to immediately institute a plan for implementing the first phase of new regulatory measures to ...

The Food and Drug Administration issued a warning on Monday advising pregnant women not to take valproate sodium products. Studies have shown that the medication can cause decreased IQ scores in ...

In an animal study, researchers found that valproate, a common epilepsy drug, possessed hypnotic and antiepileptic properties during sleep, suggesting that the drug could help improve sleep quality ...

Other effective medicines are available for epilepsy and bipolar disorder and valproate should only be used if these don’t work or aren’t suitable for an individual patient. Image Credit: Medicines ...

An 18-year-old woman presented to hospital with a 2-day history of decreased consciousness, nausea and vomiting. She had started taking valproate (750 mg/d) 2 weeks before for the treatment of ...