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New research shows a common skin fungus can help melanoma spread by changing cancer cell movement and energy use.

Zanzalintinib is an investigational oral agent that inhibits tyrosine kinase receptors associated with cancer growth, including TYRO3, VEGF, MET, AXL, and MER.

Ivonescimab's BLA acceptance is a milestone for PD-1/VEGF bispecific antibodies in the U.S., potentially transforming ...

The FDA accepted an application for ivonescimab with chemotherapy for patients with lung cancer driven by EGFR changes after ...

Adding the VEGF inhibitor ramucirumab (Cyramza) to the EGFR inhibitor osimertinib (Tagrisso) slowed progression of untreated EGFR-positive non-small cell lung cancer (NSCLC) by 9 months compared with ...

Predictive value of PIK3CA mutations for response to CDK4/6 inhibitors in hormone receptor-positive, HER2-negative metastatic breast cancer: A systematic review and meta-analysis. This is an ASCO ...

Compared with the more questionable evidence presented in the risk of CRC and functionality sections of this review, the possible prognostic value of SNPs in the VEGF-A gene in CRC appears more ...

The literature presented in this review does not indicate a clinically relevant relationship between genetic variations in the VEGF system and the risk of CRC. Hence, these markers will probably not ...