Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular ...

Knowing which lysosomal proteins are enriched in which brain cell types will help better understand contribution to neurological disorders.

Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder. Ali Ghoochani, Julia C. Heiby, Eshaan S. Rawat, Uche N. Medoh, Domenico Di Fraia, ...

What do cells do when they are “hungry”? Eukaryotic cells cope with starving conditions by eating their own components, a process called autophagy. Aa Aa Aa Normally, when you are hungry you look for ...

Lysosomes are membrane-bound organelles whose acidic lumen (pH 4.5–5.0) is required for degradation. This luminal acidity is ...

Indian biologist Yamuna Krishnan is using DNA-based nanotechnology to investigate the inner workings of human cells, potentially revolutionizing disease diagnosis and treatment.

New research, published today in the journal Science, shows how lysosomes — organelles that act like cells’ waste disposal system — respond to stress by becoming abnormally bloated, a process called ...

Janelia researchers have uncovered a novel way that two of the structures inside cells—the endoplasmic reticulum (ER) and lysosomes—coordinate the production of proteins, highlighting how interactions ...

Together with colleagues from Stanford University, USA, researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) have, for the first time, created a comprehensive cell ...

Hutchinson-Gilford progeria syndrome (HGPS) is a rare progeroid disorder, featured with premature skin wrinkling, lack of skin elasticity, absence of subcutaneous fat, alopecia, atherosclerosis and ...