Individuals with β-thalassemia develop progressive systemic iron overload, resulting in high morbidity and mortality. These complications are caused by labile plasma iron, which is taken up by ...

Incorporating structural constraints into pharmacokinetic studies of iron sucrose formulations. Results from assays conducted independently of one another can produce findings that are incompatible ...

A new study led by researchers at the Graduate Entry Medical School (GEMS), University of Limerick (UL) has found that people with low levels and very high levels of a commonly measured laboratory ...

The blood brain barrier (BBB) exists to protect the brain from pathogens and other toxins but makes central nervous system (CNS) diseases hard to treat with conventional drugs. For example, many ...

What Is a TIBC Blood Test? A total iron-binding capacity test is a blood test that tells you how much iron is binding to the transferrin in your blood, which tells you how well iron is functioning in ...

For decades scientists have sought a way to sneak large drugs across the blood-brain barrier. These efforts received a boost in 2011, when researchers led by Ryan Watts at Genentech, South San ...

Medizinische Universitätsklinik Freiburg, Abteilung Rehabilitative und Präventive Sportmedizin, Hugstetter Str 55, 79106 Freiburg, Germany Correspondence to: Dr Schumacher, Abtlg RP Sportmedizin, ...

Researchers have identified that a glycoprotein known as transferrin may critically contribute to severe forms of COVID-19. The University of Kent's School of Biosciences and the Institute of Medical ...

Over the last three decades, scientists have devised molecular shuttles that slip enzymes, antibodies, and other molecules into the central nervous system (CNS) by attaching them to the transferrin ...