To study how a key chemical neuromodulator affects signaling in the brain's cortex, Garrett Neske, PhD, has received a three-year, $300,000 grant from the Whitehall Foundation, a nonprofit ...

Ketamine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that produces rapid antidepressant action in some patients with treatment-resistant depression. However, recent data ...

Increased levels of bioactive lipids produced naturally in the body, which affect excitatory transmission between brain cells, promote mental disorders. However, this mechanism can be rebalanced by ...

Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...

Neurons intertwine with small blood vessels in the brain, but how do the two communicate? With elaborate three-dimensional reconstructions of electron microscopy images, scientists led by Jie-Min Jia, ...

A) Taste tissue of wild-type mice and taste cell synaptic dysfunction mice (SNAP-cKO). In SNAP-cKO mice, the number of sour-sensing cells is reduced. B) Gustatory nerve responses to various taste ...