Research co-led by King's College London and Sidra Medicine, Qatar, has produced the most detailed map to date of large-scale ...

Genomic structural variants (SVs) involve the rearrangement of DNA sequences and have the potential to drive phenotypic changes across the tree of life. The discovery of structural variation dates ...

Researchers still do not have a comprehensive picture of the factors that influence gene expression in human cancers. Understanding gene expression in cancer is important because it can reveal how the ...

Chong’s study, “Deciphering the exact breakpoints of structural variations using long sequencing reads with DeBreak,” was recently published in Nature Communications. UAB researchers have developed a ...

A substantial chromosomal inversion in the DG1 promoter upregulates its expression. It gives rise to a double-grain spikelet trait remarkably augmenting the grain number and yield in sorghum and ...

Researchers at Dana-Farber Cancer Institute collaborated with multiple institutions to pinpoint rare germline structural variants as risk factors for non-blood-related cancers in children, including ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought. The ...

Genome assemblies from 65 individuals, representing a variety of the world’s populations, are advancing the scientific exploration of complex genetic structural variation. Structural variations are ...

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.