Avenue Biosciences technology collects data sets on how specific signal peptides impact specific protein targets.
Inside the race to turn one of cell biology’s least understood processes into a new foundation for drug development and ...
Medical Device Network on MSN
Enodia raises seed funding to advance protein degradation platform
Enodia Therapeutics has raised €20.7m ($25m) in seed funding to advance a small-molecule platform for targeted protein ...
The endoplasmic reticulum (ER) and the secretory pathway are central to the orchestration of intracellular protein trafficking and lipid homeostasis. These dynamic systems comprise a network of ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
A novel reporter protein has been developed to enable the investigation of protein biogenesis in the ER and its disruption in disease. A recent research collaboration between multiple Japanese ...
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...
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