Receptors are specialised membrane‐bound proteins that play a fundamental role in translating extracellular signals into precise intracellular responses. Integral to cellular communication, these ...
Glucocorticoid receptors (GRs) are ligand-activated transcription factors that play a pivotal role in mediating the effects of endogenous and synthetic glucocorticoids. These receptors regulate a ...
Although scientists can learn a lot from cell culture and animal models, they cannot truly substitute for all parts of the human body, especially the brain. But scientists have now used human brain ...
Edited by Karen Young Kreeger J.A. Bennett, R. Dingledine, "Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop," Neuron, 14:373-84, ...
The research is a continuation of her 15 years of study of NMDA receptors and focuses on investigating how subtle changes in the receptor structure causes them to produce altered electrical signals.
A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...
New Cell-Based Assays Support Drug Discovery Across the Amylin Receptor Family STATE COLLEGE, PA, UNITED STATES, ...
"I think PAGER has potential for impact, both in the G protein coupled receptor biology field, and in synthetic circuits or cell-based therapies," said Alice Ting, professor of genetics at the School ...
Our bodies have to sense our environment, and receptors are one part of the sensory experience of the body. Receptors, such as those in taste buds, can interact with specific things in the environment ...
All over the body are tiny sensors called nociceptors whose job is to spot potentially harmful stimuli and send warning ...
Portage Biotech, Inc. has announced the re-launch of its subsidiary, Cyncado Therapeutics, which will operate independently to focus on developing adenosine receptor antagonists aimed at improving ...