Objective: To assess health care practitioners' ability to correctly measure the QT interval, and to identify factors and medications that may increase the risk of QT-interval prolongation and ...

Similarly, subjects with an increased QT dispersion (QTd), which may mirror discrepant repolarization characteristics of different areas of the heart, show an increased cardiovascular mortality and ...

Tyrosine kinase inhibitors (TKIs) are associated with prolongation of the QTc interval on the electrocardiogram (ECG). The QTc-interval prolongation increases the risk of life-threatening arrhythmias.

"The net increase in QT interval caused by grapefruit among healthy volunteers was small, but in the range that, if grapefruit juice were a new drug in development, the results of the present study ...

Results to be Included in BYDUREON™ New Drug Application Resubmission in the Third Quarter of 2011 SAN DIEGO & INDIANAPOLIS & WALTHAM, Mass.--(BUSINESS WIRE)-- Amylin Pharmaceuticals, Inc. (Nasdaq: ...

Having access to less intrusive QT interval measurement with flexibility around the time and place of the appointment is important 3.1 Psychiatric service user experts explained that it is important ...

Drinking large quantities of grapefruit juice may prolong the QT interval, especially in women and those who already have long QT syndrome (LQTS), new research suggests. Investigators at Tel Aviv ...

Grapefruit juice is already listed as a substance to avoid when taking QT-prolonging medications because it increases the toxicity of many drugs. Investigators have now confirmed the QT-prolonging ...

Research confirms that grapefruit juice prolongs the QT interval; this finding has implications for patients taking medications that prolong the QT interval and may have implications for patients with ...

The QT interval represents the amount of time the heart's electrical system takes to repolarize, or recharge, after each beat (i). As prolongation of the QT interval may increase the risk for cardiac ...