Acute Intermittent Porphyria (AIP) is a rare genetic disorder that has gained increasing attention in recent years. It stems from a deficiency in the enzyme porphobilinogen deaminase, leading to an ...

Patients with symptomatic acute hepatic porphyria were found to be at greater risk of accessing long-term sick leave and disability pension compared with the general population, but were not shown to ...

A mutation that impacts an enzyme involved in heme biosynthesis causes porphyrias, which are inheritable metabolic disorders. There are different types of porphyrias based on the specific enzyme ...

Porphyria is a group of genetic disorders that result in built-up of chemicals called porphyrins in the body. Porphyrins are normally converted into heme, a constituent of hemoglobin with the help of ...

Acute hepatic porphyria (AHP) refers to a family of rare genetic diseases that affect the production of heme, a component of red blood cells. It can cause life threatening complications. AHP can cause ...

Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the ...

The treatment you'll get for acute hepatic porphyria (AHP) depends on your symptoms. No matter which treatment plan you and your doctor decide on, the goal is to ease symptoms and prevent ...

Acute intermittent porphyria (AIP) is a rare condition that causes an enzyme deficiency. This can cause a person to experience abdominal pain, nausea, vomiting, and seizures. Porphyrias are rare ...

RNA interference (RNAi) specialist Alnylam has hit the accelerator on its candidate drug for ultrarare porphyria diseases, prepping for phase 3 trials later this year after unveiling initial results ...

Induction of delta aminolevulinic acid synthase 1 (ALAS1) gene expression and accumulation of neurotoxic intermediates result in neurovisceral attacks and disease manifestations in patients with acute ...

A team of researchers has discovered a molecular missing link that helps explain why fasting brings on acute attacks of the genetic disease hepatic porphyria, according to a new report in the 26 ...