Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...
Discovered in the 1970s, tumor suppressors are among the most important proteins in the body. A master regulator of growth -- "the guardian of the genome" -- the p53 protein monitors cell growth for ...
Figure 8: Regulation of ALDH3A1 and NECTIN4 by p53. Researchers Jessica J. Miciak, Lucy Petrova, Rhythm Sajwan, Aditya Pandya, Mikayla Deckard, Andrew J. Munoz, and Fred Bunz from the Sidney Kimmel ...