Figure 8: Regulation of ALDH3A1 and NECTIN4 by p53. Researchers Jessica J. Miciak, Lucy Petrova, Rhythm Sajwan, Aditya Pandya, Mikayla Deckard, Andrew J. Munoz, and Fred Bunz from the Sidney Kimmel ...
Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...
Researchers have uncovered a mechanism that allows breast cancer to send metastases to the brain, potentially enabling the ...
The discovery could pave the way for new treatments, improved risk prediction, and earlier intervention for brain metastases.
Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for therapeutics. Among them, the Y220C mutation is the ninth most frequent and it ...
A research team at the University of Konstanz, led by toxicologist Ivano Amelio, has demonstrated how differently individual mutations of the tumor suppressor p53 affect pancreatic carcinomas. When ...
GMCL1-dependent degradation of 53BP1 suppresses mitotic surveillance, tuning p53 activation thresholds that govern cell fate decisions and cellular responses after mitosis.
From new imaging and targeted therapies to patient journeys, 2025 highlighted key advances and personal stories in lung ...
Add Yahoo as a preferred source to see more of our stories on Google. Cancer Cell Spread and oncology or Malignant Cancerous Growth and Metastasis anatomy concept as growing tumor cells and Malignancy ...
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