Bone remodelling takes place in specialized modelling units spread throughout the skeleton and involves bone resorption by mature osteoclasts, followed by differentiation of osteoblast precursors to ...
Osteocytes, the most abundant cells in bone tissue, have long been underestimated in their functional capacity. Traditionally viewed as passive entities, recent research has illuminated their pivotal ...
Researchers led by Kanazawa University show that messages sent by osteoblasts via extracellular vesicles trigger the formation of mature osteoclasts during fracture healing Kanazawa, Japan - In a ...
Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown. Now, researchers at Osaka University established ...
Osteoblasts act in a group to make bone over the course of several months. However, how osteoblasts cooperate with each other in vivo is still unknown. Now, researchers at Osaka University established ...
Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...
In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers has now identified an enzyme that controls the activity of osteoblasts. An ...
Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation, a new study has found.
Researchers from Osaka University have identified a gene underlying the development of osteoporosis and developed a new mouse model, pointing the way for future treatments and a greater understanding ...