Iron catalyst drives asymmetric 1,6 addition of aliphatic Grignard reagents to α,β,γ,δ-unsaturated carbonyl compounds

Scientists at the Institute of Science Tokyo (Science Tokyo) have successfully realized the highly selective asymmetric 1,6 ...
Nature

Organic–inorganic supramolecular solid catalyst boosts organic reactions in water

Coordination polymers and metal-organic frameworks are appealing as synthetic hosts for mediating chemical reactions. Here we report the preparation of a mesoscopic metal-organic structure based on ...
C&EN

Addition Against The Grain

With the help of zinc reagents, chemists have found a loophole in rules that govern additions to chiral carbonyl compounds, a fundamental reaction in organic synthesis. The work, presented on March 24 ...
EurekAlert!

Using LoRA models to predict multiple types of organic reactions

Figure 1. LoRA-Chem: From Model Customization to Organic Chemistry Reaction Tasks. (a) Several machine learning algorithm paradigms applied to organic chemistry. (b) Inspired by AI-driven image style ...
Science Daily

New insights into how the most iconic reaction in organic chemistry really works

The Diels-Alder reaction is the most iconic organic chemistry reaction. Scientists now report on exactly how this chemical reaction, discovered in 1928, occurs. In 1928, chemists Otto Diels and Kurt ...
C&EN

Podcast: Chemists debate the value of name reactions in organic chemistry

Scientists have been naming ideas, theorems, discoveries, and so on after other scientists for a very long time (Newton’s laws of motion, anyone?). Chemists are no different. They’ve been naming ...