A University of Calgary-led international research team has identified a genetic factor that may explain why people respond so differently to opioid pain medications, and why some individuals face ...

A University of Calgary-led international research team has identified a genetic factor that may explain why people respond so differently to opioid ...

Millions of people take opioids for chronic back pain, but many of them get limited relief while experiencing side effects and worrying about the stigma associated with taking them, suggests research ...

The new method is designed to focus specifically on pain-related signals, without interfering with normal activity in other parts of the brain. A new preclinical study has identified a gene therapy ap ...

Understanding both sides of this medication is essential before starting or continuing to take it.

Choosing the right opioid for an older adult can be challenging for a number of reasons, including comorbidities, polypharmacy, physiological changes, and cognitive and communication challenges. For ...

Kappa-opioid receptor (KOR) agonists represent a promising class of compounds that modulate pain, mood and various neurobehavioural processes. Unlike traditional opioids that primarily target the ...

Epidermal growth factor receptor (EGFR) signaling in the tissue around oral cancers both increases nerve sensitivity and ...

Rutgers has granted Tonix Pharmaceutical exclusive worldwide rights to develop and commercialize a novel class of compounds ...

Naltrexone is a generic prescription drug used to treat certain substance use disorders. Naltrexone oral tablet does not come in any brand-name versions. This drug can cause mild to serious side ...