The anti-tumor immune response involves a series of complex steps mediated by various immune cells and signaling molecules.

Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor immunity. This review synthesizes emerging mechanistic evidence showing that ...

The major histocompatibility complex (MHC) region plays a crucial role in immune function; therefore, any genetic or epigenetic polymorphisms within the MHC locus may result in various diseases, as ...

MHC class II molecules are central to the adaptive immune response, serving as the means by which antigen-presenting cells, notably dendritic cells, display processed peptides to CD4+ T cells. This ...

The result is one molecule that can be both a checkpoint degrader and a cancer vaccine ( Nature 2026, DOI: 10.1038/s41586-025 ...

ProImmune Ltd, a global leader in life science reagents and services, today announced the launch of its new ProVE ® SL Self-Loading MHC Class I Monomers. The novel reagents for antigen-specific CD8+ T ...

Modifying the organ instead of the recipient isn’t a new idea, but it is an important one, said Jeffrey Platt, a transplantation biologist at the University of Michigan Medical School who was not ...

ProImmune Ltd, a global leader in life science reagents and services, today announced the launch of its new ProVE® SL Self-Loading MHC Class I Monomers. The novel reagents for antigen-specific CD8+ T ...