The Mfd protein repairs bacterial DNA, but can also, to scientists' surprise, promote mutation. Bacterial mutations can lead to antibiotic resistance. Understanding this second "role" of the Mfd ...
A bacterial protein long thought of only as a safeguard against DNA damage also serves a more general housekeeping function during normal growth, researchers from the University of Wollongong have ...
(A) Mfd repair function. 1. An RNA polymerase is blocked by UV damage in DNA. 2. Mfd binds to RNA polymerase and DNA, and moves along the DNA to remove the RNA polymerase from the DNA. 3. By removing ...
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