Brensocatib, newly approved by the FDA for noncystic fibrosis bronchiectasis (NCFB), was also associated with improvements in lung structure, on the basis of data from a substudy of 100 individuals ...

Brensocatib, a DPP1 inhibitor, is the first FDA-approved therapy for non-cystic fibrosis bronchiectasis, showing significant clinical and structural benefits. The ASPEN trial demonstrated that ...

Previously linked to the severity of asthma and chronic obstructive pulmonary disease in humans, vitamin D deficiency has now been shown to alter lung structure and function in young mice. The new ...

The most important lung function is to take oxygen from the environment and transfer it to the bloodstream. Lung function tests can show how well the lungs carry out this task. The left and right ...

Respiratory diseases are a challenging problem to treat. Inhalable medicines are a promising solution that depend on the ability to deliver tiny particles known as aerosols to the correct location in ...

Alveoli are tiny air sacs in your lungs that take up the oxygen you breathe in and keep your body going. Although they’re microscopic, alveoli are the workhorses of your respiratory system. People ...

In 1985, we hypothesized that a living vital organ could be rationally designed and built for human therapy from cells and degradable polymer scaffolding. This was based on only two pieces of previous ...