Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

A brain circuit involving leptin allows mice to carry out vital behaviors, such as eating and sleeping, during anxious episodes. A study led by researchers at the University of Cologne and University ...

Leptin is an adipose tissue hormone that regulates energy and metabolic balance by activating the leptin receptor (LEPR). An imbalance in leptin or LEPR signalling — whether through hyperleptinemia or ...

A paper published in the May issue of Diabetes implicates triglycerides in the mechanism of leptin resistance. These fats, elevated in obesity, are what disrupt the transport of the hormone across the ...

A deep dive into the scientific shift toward multi-target obesity therapeutics and its implications for metabolic health and disease prevention.

Your defended weight range can gradually shift upward through hormonal, metabolic, environmental, and microbiome-driven changes that push the body toward higher weight. Questions about why weight gain ...

Reduced availability of leptin, a hormone that helps you maintain a healthy weight by regulating your appetite and helping to maintain energy balance, has been found to play a role in the development ...

Most people think of weight loss as a math problem: calories in versus calories out. In reality, your body sees it as a survival threat. When calorie intake falls or body fat decreases, biological ...