A pair of USC Stem Cell mouse studies detail how progenitor cells self-renew, differentiate, and aggregate into early kidney structures, offering insights for the creation of stem cell-based ...

This is the longest-lived set of developing kidney organoids derived from tissue stem cells The kidney developed over a half a year, enabling real-time observation, gene isolation for birth defects ...

Zebrafish have emerged as a pivotal vertebrate model for studying kidney development, owing to the high genetic and morphological conservation with mammalian systems. The process of nephrogenesis in ...

Using CRISPR-based engineering methods to prompt stem cells to organize into embryo-like structures, scientists were able to create 'programmable' cellular models of embryos without ever experimenting ...

The role of Fibroblast Growth Factor 8 (FGF8) in embryonic development and organ formation is gaining increased recognition as scientists uncover its wide-ranging influence. FGF8, a powerful signaling ...

Researchers have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization, each cell has the ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

What do the earliest stages of a pregnancy look like? Embryonic development has been extensively studied, but most of our knowledge of the earliest stages of a growing baby come from stationary ...

Cell division is an essential process for all life on earth, yet the exact mechanisms by which cells divide during early embryonic development have remained elusive – particularly for egg-laying ...

For the first time, researchers from both Sheba Medical Center and Tel Aviv University have grown human kidney organoids (a synthetic 3D organ culture) from tissue stem cells in the laboratory, ...