As we get older, chemical marks on our DNA slowly shift. Now, a study reveals this 'drift' in gut stem cells is fueled by ...

Crypt-base-columnar cells are continuously dividing intestinal stem cells that generate IECs, which are composed by distinct specialised cell types that play different functions: Enterocytes (in the ...

Although the gut renews itself constantly, its stem cells accumulate age-related molecular changes that quietly alter how ...

Chemical and Biological Engineering PhD student Max Yavitt is the lead author on a new paper in Science Advancesthat focuses on intestinal tissue research. The work could allow researchers to control ...

The study, “A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts,” was published in Immunity. The team, led by Carlene L. Zindl, Ph.D., found that IL-22 ...

Pythons may hold the answer to another way to regrow our guts, a group of researchers led by the University of Texas at Arlington finds. In a recent study published in the journal Proceedings of the ...

During drug development, researchers need to perform adequate nonclinical testing to ensure a drug’s safety and efficacy before starting clinical trials. An important aspect they must evaluate is a ...

Researchers at the University of Gothenburg have now shown how mucus protects the small intestine in mice. In the future, this finding may lead to new ways of preventing relapse in Crohn’s disease in ...

Our intestine plays a vital role in absorbing nutrients and provides a protective barrier within the digestive tract. As a consequence of these functions, the epithelial cells lining the intestine are ...