Dihydropteroate synthase (DHPS) is a crucial enzyme in the folate biosynthetic pathway, catalysing the formation of essential folate cofactors that underpin DNA synthesis and cellular functioning.
Amsterdam, the Netherlands - The arrival of multiple new drugs for treating rheumatoid arthritis (RA) presents rheumatologists with the challenge of learning how best to combine these agents. An in ...
Since the 1940s, inhibitors of thymidylate biosynthesis have remained among the most effective chemotherapies used in the treatment of cancer The enzyme thymidylate synthase (TS) is a key metabolic ...
An international paper on folate biomarkers is part of an initiative to provide evidence-based guidance for the global nutrition and public health community. The comprehensive study on folate, an ...
Westbury, NY - Aug. 15, 2019 - BioIVT, a leading provider of research models and services for drug and diagnostic development, today announced that researchers in its Transporter Sciences Group have ...
Megaloblastosis appeared in a patient receiving pyrimethamine. Pyrimethamine seemed to act as does the folate antagonist methotrexate in short-term in vitro culture of the patient's bone marrow. It ...
Although they number from 1 (thiamine) to 12 (cobalamin), there are eight B vitamins—don't bother seeking numbers 4, 8, 10, or 11. The rest are all facilitators of the nervous system and tend to work ...
There are various kinds of vitamins, of which Folate is considered to be an important kind. It is more commonly known as Folic Acid or Vitamin B9, a nutrient whose deficiency is often linked to hair ...
Although they number from 1 (thiamine) to 12 (cobalamin), there are eight B vitamins—don't bother seeking numbers 4, 8, 10, or 11. The rest are all facilitators of the nervous system and tend to work ...
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