In 1962, Pitcock et al 12 published their findings in adults with myelofibrosis. Renal extramedullary hematopoiesis was recognized in 35% of autopsies. In this series of 17 complete autopsies, the ...

Patients with solid tumors, such as breast and gastrointestinal cancers, who also have clonal hematopoiesis of indeterminate potential could have a significantly higher risk for cardiovascular disease ...

Nagase and colleagues recently described a mouse model of CHIP and its transformation to a model of acute myeloid leukemia. 5 An Asxl1 mutation causes CHIP (Panel A) and leads to epigenetic ...

In a recent study published in the journal Nature Genetics, a team of researchers from the United Kingdom (U.K.) and the United States (U.S.) analyzed whole blood samples from a large cohort of U.K.

New insights reveal how hidden genetic mutations could be silently fueling heart disease in middle-aged adults, paving the way for personalized prevention strategies. In a recent study published in ...

Randomized, Double-Blind, Phase III Study of Fosnetupitant Versus Fosaprepitant for Prevention of Highly Emetogenic Chemotherapy-Induced Nausea and Vomiting: CONSOLE Donor CH is closely associated ...

Researchers from the University of Toronto (Canada) have presented a new high-resolution gene expression atlas that shows the normal differentiation process of hematopoietic cells at the American ...

Intratumoral Transcriptome Heterogeneity Is Associated With Patient Prognosis and Sidedness in Patients With Colorectal Cancer Treated With Anti-EGFR Therapy From the CO.20 Trial A range of zero to ...