Translational medicine researchers used the Mimetas® human kidney glomerulus-on-a-chip to investigate potential pharmaceutical interventions for patients with a severe kidney disease called focal ...

Kidneys work to constantly filter blood and remove toxins from the body. Conditions such as chronic kidney disease (CKD) are characterized by a reduced ability to perform this essential function. CKD ...

Our kidneys are charged with the extraordinary task of filtering about 53 gallons of fluid a day, a process that depends on podocytes, tiny, highly specialized cells in the cluster of blood vessels in ...

A study published in Advanced Healthcare Materials describes the bioengineering of three-dimensional (3D) kidney glomerular microtissues that replicate the glomerular filtration barrier (GFB) ...

Researchers have developed the first model of kidney filtration in the lab that accurately mimics human kidney physiology. The model represents a leap in chronic kidney disease research and could help ...

Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental factors, as well as existing medical conditions. Known genetic risk factors for ...

Chronic kidney disease (CKD) is a progressive condition in which the kidneys gradually lose their ability to filter waste from the blood. It is a common health concern that affects an estimated 8–16% ...

An image of a mouse kidney glomerulus taken on a fluorescence microscope showing cell nuclei in blue, the PIEZO2 gene in magenta, and the renin gene in green. Each dot represents a single mRNA ...

CCL5 protects podocytes, the kidney’s essential filtration cells, but simultaneously drives harmful inflammation. Ultimately, these damaging effects surpass its protective role, leading to progressive ...