Treating cancer with medicines that tightly attach to their targets via covalent bonds is not a new concept in drug discovery, but it is picking up pace. Some companies are trying to improve this ...

New research shows that curium — one of the heaviest known elements — can be manipulated to a larger degree than previously thought. An international team published a study on July 15 in the journal ...

In the realms of supramolecular chemistry, crystal engineering, and biology, noncovalent interactions play a critical role in shaping three-dimensional structures. Hydrogen bonds are the most well ...

Covalent organic frameworks (COFs) are versatile materials composed of interconnected organic molecules held together by covalent bonds. These frameworks can be constructed in two-dimensional or three ...

Uranium forms an unusually strong triple covalent bond with nitrile groups, confounding predictions about the bond strength of actinides compared with the remainder of the periodic table. Elements ...

Researchers have found a new type of cross-link between amino acids in a protein (Nature 2021, DOI: 10.1038/s41586-021-03513-3). The intramolecular linkage is an N-O-S bridge formed by oxidizing the ...

A research group has successfully demonstrated that carbon-carbon (C-C) covalent bonds expand and contract flexibly in response to light and heat. This unexpected flexibility of C-C bonds could confer ...