Stem cell subpopulation found to be essential for bone fracture repair

In a study published in Cell Research, researchers have identified a fibrous-layer resident subpopulation of P-SSCs labeled ...
News-Medical.Net

Study identifies Apex1 as a redox-regulated driver of fracture repair

Bone fractures usually heal efficiently, but in some patients this process fails, causing nonunion. A recent study identifies ...
AlphaGalileo

Why Some Broken Bones Fail to Heal: Scientists Reveal a Critical Molecular Trigger

Bone fractures usually heal efficiently, but in some patients this process fails, causing nonunion. A recent study identifies ...
JSTOR Daily

Simulation of the Initial Stage of Endochondral Ossification: In vitro Sequential Culture of Growth Cartilage Cells and Bone Marrow Cells

Growth cartilage cells were isolated from the ribs of young rats and cultured at high cell density in Ham's F-12 medium supplemented with 10% fetal calf serum. During 7 days, glycosaminoglycans and ...
JSTOR Daily

Chronic psychosocial stress compromises the immune response and endochondral ossification during bone fracture healing via β-AR signaling

Melanie Haffner-Luntzer, Sandra Foertsch, Verena Fischer, Katja Prystaz, Miriam Tschaffon, Yvonne Mödinger, Chelsea S. Bahney, Ralph S. Marcucio, Theodore Miclau, Anita Ignatius, Stefan O. Reber ...
Acsh.org

Endochondral ossification

"Historically viewed as mainly a “wear and tear” condition, new insights suggest that OA may be part of an evolutionary, age-related biological process rather than mainly driven by mechanical damage." ...