Researchers have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization, each cell has the ...

In mammals, signalling between the placenta and the embryo is essential for successful development. Here, a quantitative, time-resolved model describes the coordinated formation of the mouse embryo ...

Researchers have uncovered how egg cells prepare for the creation of life. Their work reveals the secrets of the Balbiani body (Bb), a remarkable structure that organizes essential molecules to guide ...

Scientists at the University of California, Santa Cruz (UCSC), used CRISPR to engineer cellular models of embryos that mimic what happens in the first few days after reproductive cells meet. These ...

Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology. Pluripotent stem cells (PSCs) have been invaluable ...

A research team led by Associate Professor Hirofumi Nishizono and graduate student Masaki Kato from the Research Support ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

Researchers have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four weeks after fertilization. This is ...

In the earliest hours after fertilization, an embryo takes its first steps toward becoming a living organism by shedding maternal control and activating its own genetic program. This critical process, ...

For several years, researchers studied human embryonic stem cells (ESCs) to understand the unique features of these pluripotent cells, but on their own, they poorly resembled the complex structures ...