Retinoic acid suppresses immune defenses against cancer, but a new drug KyA33 boosts vaccine success and slows tumor growth ...

MHC class II molecules are central to the adaptive immune response, serving as the means by which antigen-presenting cells, notably dendritic cells, display processed peptides to CD4+ T cells. This ...

Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s ...

Cancer immunotherapy is a strategy that turns the patient’s own immune cells into a “search-and-destroy” force that attacks the tumor’s cells. The “search” immune cells are the dendritic cells, which ...

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A—all-trans retinoic ...

LMU researchers have shown that a particular type of immune cell acts more flexibly than previously thought - with potential for new therapeutic approaches. As part of the innate immune system, ...

New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides through a dendritic cell-like pathway that may shape early coeliac ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...