Johns Hopkins Medicine

Detecting Early-Stage Cancers with a New Blood Test Measuring Epigenetic Instability

@hopkinskimmel researchers develop novel liquid biopsy approach to identifying early-stage cancers. › ...

Cells' built-in capacity limit for copying DNA could impact cancer treatment

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...
ascopubs.org

Detection of Molecular Residual Disease by Circulating Tumor DNA in Early-Stage Node-Negative Rectal Cancers (CCTG CO.28) Using a Tumor-Informed Assay

PolyPEPI1018 Cancer Vaccine and TAS-102 for Patients With Advanced, Chemo-Refractory, Microsatellite-Stable Metastatic Colorectal Cancer: A Phase Ib Nonrandomized Study ctDNA was detected in 24.5% of ...
ascopubs.org

Combined Analyses of Circulating Tumor DNA and Immunoscore in Patients With Stage III Colon Cancer: A Post Hoc Analysis of the PRODIGE-GERCOR IDEA-France/HORG-IDEA-Greece Trials

First-Line Mobocertinib Versus Platinum-Based Chemotherapy in Patients With EGFR Exon 20 Insertion–Positive Metastatic Non–Small Cell Lung Cancer in the Phase III EXCLAIM-2 Trial Plasma samples were ...
Nature

DNA Replication and Checkpoint Control in S Phase

During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a connector ...