This double-blind trial enrolled adults with HIV-associated cryptococcal meningitis in Vietnam, Thailand, Indonesia, Laos, Uganda, and Malawi. All patients received combination antifungal therapy of ...

As a result of a large randomized, controlled trial (and experience during the first 15 years of the AIDS epidemic), standard guidelines for treatment of cryptococcal meningitis recommend 2 weeks of ...

Meningitis is an infection affecting the membranes that line the skull and spinal cord. Cryptococcal meningitis is a type of meningitis caused by a fungus called Cryptococcus. This type of meningitis ...

Cryptococcus is a yeast, which is a kind of fungus. This yeast infects those with poor immunity, like people with HIV. Cryptococcus has a liking for the nervous system, and it often causes meningitis ...

A common first-line treatment approach for cryptococcal meningitis in low-income countries is being compromised by the emergence of drug resistance, new University of Liverpool research warns.

Cryptococcal meningitis is a leading cause of human immunodeficiency virus (HIV)–related death in sub-Saharan Africa. Whether a treatment regimen that includes a single high dose of liposomal ...

Hopes that tamoxifen could improve survival for a deadly form of fungal meningitis have been dashed by clinical trial results published in eLife. The study finds that adding tamoxifen to standard ...

Crytococcal meningitis is a deadly invasive fungal infection which affects hundreds of thousands of HIV patients in the late stage of their disease every year. Crytococcal meningitis is a deadly ...

Several immune cells help fungi infect the brain and cause meningitis when they should be doing the exact opposite. From the University of Sydney, researchers investigate the immune system’s ...

Dar es Salaam / Lilongwe / Geneva — 15 April 2025 — A new, easier-to-administer and patient-friendly sustained-release formulation of flucytosine, a medicine used to treat cryptococcal meningitis, has ...

Cryptococcus neoformans and Cryptococcus gattii have been found large numbers on trees in South Africa. Large populations of potentially deadly cryptococcal fungi have been found on woody debris ...