A newly identified and rare genetic variant slows the growth of mutated blood stem cells and reduces the risk of leukemia.

The blood system changes over time: a subset of stem cells outcompete their neighbors and gradually take over blood production. In addition, the blood stem cell reservoir shrinks and becomes dominated ...

Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele frequencies ...

A newly identified and rare genetic variant slows the growth of mutated blood stem cells, researchers report, and it reduces the risk of leukemia. The findings offer insight into why some people are ...

MILAN — Is chronic lymphocytic leukemia (CLL) progression primarily driven by genetic mutations or by external cues from the tumor microenvironment? Despite major strides in targeted therapies, CLL ...

Gastrointestinal (GI) cancers represent a complex interplay of genetic mutations, epigenetic alterations, and environmental factors. The initiation and progression of these cancers are influenced by ...

Real-world evidence of fruquintinib (Fruq) efficacy after regorafenib (Rego) and trifluridine–tipiracil (TAS-102) in refractory metastatic colorectal cancer (mCRC).