Amyloids are typically associated with neurodegenerative diseases such as Alzheimer's, Huntington's and Parkinsons. They form tightly packed, highly stable "detrimental" protein fibers that destroy ...

Researchers say human versions of identified fruit fly chaperone proteins have been implicated in schizophrenia.

Researchers identified a chaperone protein, Funes, that triggers controlled amyloid formation in fruit fly neurons to ...

Discover how amyloid proteins help form long-term memories according to new research from the Stowers Institute.

Heat shock proteins (HSPs) and molecular chaperones are fundamental to cellular proteostasis, ensuring proteins achieve and maintain their functional conformation while preventing misfolding and ...

Neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis (ALS) affect millions of people worldwide, yet treatments remain largely limited to symptom ...

Protein folding helpers such as TRiC and prefoldin (PFD) are crucial for the correct folding of many essential proteins. In a Nature study, researchers from the Max Planck Institute of Biochemistry ...

A new study has found that treatment with a ‘chemical chaperone’ assists in reducing the accumulation of protein plaques and restores cognitive functioning in mouse models of Alzheimer’s disease. The ...