For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

A research team has identified a new mechanism that controls DNA’s ability to replicate—and thereby a cell’s ability to divide.

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During ...

New research reveals that triggering a cell’s DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no antiviral ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Prior to cell division, chromosomes are seemingly a jumbled mess. During cell division, parent cell chromosomes and their duplicates sort themselves out by condensing, becoming thousands of times more ...

Notably, inhibition of cGAS-STING from early development rescued mice from developmental lethality and premature aging caused ...

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research reveals new aspects of BKPyV replication, offering possible drug targets ...

The discovery could serve as a starting point for antiviral strategies. A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the ...