Researchers found that CD4+ T cells can be classified into 18 categories and 12 distinct gene programs, and that characteristic changes in CD4+ T cell profiles are associated with autoimmune disease, ...

Measuring CD4 T-cells is important in helping healthcare providers determine the stage and possible complications of HIV infection. While they are no longer used to determine when HIV therapy should ...

Higher levels of CD4-positive naïve T cells in patients receiving CAR T-cell therapy for multiple myeloma are associated with ...

In a recent article published in the Cell Reports Journal, researchers used a preclinical mouse model to demonstrate that T helper 1 (Th1) effector memory cluster of differentiation 4 (CD4) + T cells ...

Certain levels of urinary CD4+ T lymphocytes in patients with ANCA-associated vasculitis have a 60% and 98% sensitivity and specificity, respectively, for predicting future renal flares. Urinary CD4+ ...

The researchers concluded that the interplay between CD4 and CD8 T cells creates an anti-inflammatory environment that is hostile to Mtb and, as a result, limits bacterial growth and disease severity.

Abnormal expansion of PD-1+ T lymphocytes may be a sign of lupus nephritis onset in patients with SLE. Elevated PD-1+CD4+ T cells represent an independent risk factor for lupus nephritis (LN) and may ...