Protein aggregates, damaged organelles, and invading bacteria are identified and removed in healthy cells. An international ...
To stay healthy, our cells rely on a self-cleaning mechanism that removes defective or unnecessary components. This process, ...
When we give ourselves a break from eating, our cells wake up and repair. Researchers hope further study could pave the way ...
A research team has discovered a novel mechanism essential for initiating autophagy. The study highlights the role of ZDHHC13, an enzyme that palmitoylates ULK1, in triggering autophagy. This ...
Our immune system has various ways to deal with threats from the outside like pathogens. One of the defence mechanisms is a process called autophagy. 'You can imagine autophagy as the vacuum cleaner ...
Tomato plants use a recycling process called autophagy to stay healthy, especially during heat stress. A gene called SlATG8f ...
A new discovery from an international collaborative research team has solved the mystery of how cells turn on their recycling ...
Indian scientists found that aging is driven by failing "support cells" rather than stem cells themselves. Deteriorating ...
Upon autophagy induction, ZDHHC13 is recruited to autophagosome formation sites together with ATG9A. ULK1 is palmitoylated at Cys 927 and Cys 1003 residues by ZDHHC13, and the ULK1 complex are ...