Alpha-1 antitrypsin deficiency, AATD, is an inherited disease affecting the lung, liver, and, rarely, skin. Alpha-1 antitrypsin, AAT, is a protease inhibitor of the proteolytic enzyme elastase.

Early emphysema due to alpha 1-antitrypsin deficiency (alpha 1-ATD) in a young patient with asthma is an unusual and frequently missed diagnosis. Theoretical and clinical evidence supports the ...

Alpha-1-antitrypsin is a so-called protease inhibitor, a type of enzyme inhibitor. It is produced in the liver but exerts its effects in the lungs, where it regulates immune cell activity. This ...

As part of the multicenter National Heart, Lung, and Blood Institute registry of patients with severe deficiency of alpha 1-antitrypsin with 1,129 enrollees, this report describes measures undertaken ...

Researchers at Saint Louis University's School of Medicine, in collaboration with Arrowhead Pharmaceuticals and Takeda Pharmaceuticals, report the first effective drug to treat a rare, genetic liver ...

Alpha-1 antitrypsin deficiency (AATD) is a genetic disorder characterized by the misfolding and accumulation of the mutant variant of alpha-1 antitrypsin (AAT) within hepatocytes, which limits its ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Studies assessing bronchoscopic lung volume reduction ...

"Our findings demonstrate that dyspnea, frequent exacerbations, and other aspects of disease severity associate with worse quality of life, particularly its physical component." -- Radmila Choate, PhD ...

Korro Bio completed dosing for its KRRO-110 study in AATD, expects interim results in 2025, and has strong financial resources. Korro Bio, Inc. has completed dosing for the first two cohorts in its ...

Austin, Texas, Jan. 13, 2026 (GLOBE NEWSWIRE) -- Alpha-1 Antitrypsin Deficiency Market Size & Growth Analysis: According to SNS Insider, The Alpha-1 Antitrypsin Deficiency Market was valued at USD ...

Alpha-1 antitrypsin deficiency (AATD) is a hereditary condition characterised by the misfolding of the alpha-1 antitrypsin (AAT) protein, resulting in its hepatic accumulation and compromised protease ...